Zesty Cajun Garlic Parmesan

Featured in: Dinner Grin

This vibrant fusion pasta features tender chicken and cheese tortellini enveloped in a spicy, creamy Cajun garlic Parmesan sauce. Quick to prepare, it's ideal for weeknight dinners, boasting rich flavor from smoked paprika, heavy cream, fresh Parmesan, and aromatic vegetables. The dish comes together in under 40 minutes, offering a satisfying combination of textures and tastes. Garnish with fresh parsley and extra Parmesan for added flair. Ideal with crusty bread and a crisp white wine, this lively pasta highlights American-Italian flair with an exciting Cajun twist.

Updated on Sun, 09 Nov 2025 10:05:00 GMT
Vibrant Zesty Cajun Garlic Parmesan Chicken Tortellini served with fresh parsley garnish.  Save
Vibrant Zesty Cajun Garlic Parmesan Chicken Tortellini served with fresh parsley garnish. | grinnosh.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I first made this on a busy night when everyone wanted something comforting but not the usual. The combo of Cajun spice with Parmesan was a hit—now it&squot;s the dish my friends request most.

Ingredients

  • Chicken breasts: 2 large boneless, skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz) refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g), freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons, chopped (for garnish)
  • Extra grated Parmesan: Optional, for serving

Instructions

Cook Tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Prepare Chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 7 minutes. Remove chicken from skillet and set aside.
Sauté Aromatics:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3 4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Make Cajun Sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add Parmesan:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine Pasta and Chicken:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Heat Through:
Cook for an additional 2 3 minutes until heated through.
Serve:
Serve garnished with fresh parsley and extra Parmesan if desired.
Creamy Cajun garlic Parmesan chicken tortellini with tender pasta and rustic bell peppers.  Save
Creamy Cajun garlic Parmesan chicken tortellini with tender pasta and rustic bell peppers. | grinnosh.com

This is always a favorite for a movie night at our house—a big bowl shared around the table brings everyone together.

Serving Suggestions

Pair this pasta with crusty bread and a refreshing green salad. A crisp white wine complements the spicy creamy sauce beautifully.

Variations

Try substituting shrimp for chicken or using a spinach tortellini for a twist. For extra heat, sprinkle cayenne or red pepper flakes over each serving.

Leftover Storage

Store leftovers in an airtight container in the fridge up to 3 days. Reheat gently in a skillet with a splash of cream to keep the sauce smooth.

Sizzling Zesty Cajun Garlic Parmesan Chicken Tortellini, a rich and flavorful weeknight meal. Save
Sizzling Zesty Cajun Garlic Parmesan Chicken Tortellini, a rich and flavorful weeknight meal. | grinnosh.com

This Cajun chicken tortellini is a weeknight winner that&squot;s sure to become a family favorite.

Recipe FAQ

Can I substitute the chicken with another protein?

Yes! Shrimp makes a delicious alternative, adding a seafood twist that pairs well with the Cajun flavors.

How do I add extra heat to this dish?

Add a pinch of cayenne or red pepper flakes for additional spiciness. Adjust to your taste preference.

What type of tortellini works best?

Refrigerated cheese tortellini offers great texture and flavor, but you can use frozen or homemade as well.

Can I prepare this meal ahead of time?

Yes, you can make in advance. Reheat gently with a splash of cream to preserve smoothness in the sauce.

What sides pair well with this dish?

Serve with crusty bread to soak up the sauce, and a fresh green salad or crisp white wine for balance.

Are there dairy-free options for the sauce?

Substitute coconut cream and a vegan Parmesan to make the sauce dairy-free, though flavor will vary slightly.

Zesty Cajun Garlic Parmesan

Chicken and cheese tortellini in creamy Cajun garlic Parmesan sauce delivers bold flavor and weeknight convenience.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min
Created by Hannah Lewis


Skill level Easy

Heritage American-Italian Fusion

Output 4 Portions

Dietary guidelines None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 oz refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 1/2 cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley, for garnish
03 Optional: extra grated Parmesan for serving

Directions

Stage 01

Cook Tortellini: Bring a large pot of salted water to boiling. Add tortellini and prepare according to package directions. Drain and set aside.

Stage 02

Sauté Chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high. Add chicken pieces and season with half the Cajun seasoning, salt, and black pepper. Sauté for 5-7 minutes until browned and fully cooked. Remove chicken and set aside.

Stage 03

Sauté Vegetables: In the same skillet, add remaining olive oil and butter. Add onion and bell pepper, sauté 3-4 minutes until softened. Add garlic and cook 30 seconds until fragrant.

Stage 04

Prepare Sauce: Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in heavy cream. Bring to a gentle simmer, stirring frequently.

Stage 05

Finish Sauce: Add Parmesan cheese to the skillet and stir until melted and the sauce is smooth. Taste and adjust seasoning if needed.

Stage 06

Combine Ingredients: Return cooked chicken to the skillet along with the tortellini. Gently toss everything in the sauce to coat.

Stage 07

Heat Through: Continue cooking for 2-3 minutes until everything is heated through and well combined.

Stage 08

Serve: Plate the dish and garnish with chopped parsley and extra Parmesan if desired.

Necessary tools

  • Large pot
  • Large skillet
  • Chefs knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy details

Review each component for potential allergens and consult with healthcare professionals if you're uncertain about ingredients.
  • Contains wheat from tortellini.
  • Contains milk from cream, Parmesan, and butter.
  • Contains eggs, if present in tortellini filling.

Nutrient content (per portion)

These values are approximate guidelines only and shouldn't replace professional nutritional advice.
  • Energy: 620
  • Fats: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g